Circulating Microparticles
نویسندگان
چکیده
منابع مشابه
Circulating CD62E+ Microparticles and Cardiovascular Outcomes
BACKGROUND Activated endothelial cells release plasma membrane submicron vesicles expressing CD62E (E-selectin) into blood, known as endothelial microparticles (EMPs). We studied whether the levels of endothelial microparticles expressing CD62E(+), CD31(+)/Annexin-V(+), or CD31(+)/CD42(-) predict cardiovascular outcomes in patients with stroke history. METHODS/PRINCIPAL FINDINGS Patients with...
متن کاملCirculating Endothelial Microparticles in Diabetes Mellitus
BACKGROUND Endothelial Microparticles (EMPs) are small vesicles shed from activated or apoptotic endothelial cells and involved in cellular cross-talk. Whether EMP immunophenotypes vary according to stimulus in Diabetes Mellitus (DM) is not known. We studied the cellular adhesion molecule (CAM) profile of circulating EMPs in patients with and without Diabetes Mellitus type 2, who were undergoin...
متن کاملCirculating microparticles in systemic Lupus Erythematosus.
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease presenting with a wide array of clinical manifestations and an elusive pathogenesis. A characteristic feature in SLE is the occurrence of autoantibodies against chromatin, double-stranded DNA, and RNA-binding ribonucleoproteins. Observations of defective clearance of dying cells in SLE combined with the generation and exposure ...
متن کاملPhysiologic Impact of Circulating RBC Microparticles upon Blood-Vascular Interactions
Here, we review current data elucidating the role of red blood cell derived microparticles (RMPs) in normal vascular physiology and disease progression. Microparticles (MPs) are submicron-size, membrane-encapsulated vesicles derived from various parent cell types. MPs are produced in response to numerous stimuli that promote a sequence of cytoskeletal and membrane phospholipid changes and resul...
متن کاملCirculating microparticles: a potential prognostic marker for atherosclerotic vascular disease.
Although the presence of subcellular procoagulant particles in highly centrifuged plasma has been known for many years, it was not until 1967 that shed membrane procoagulant fragments from activated platelets were described by Wolf 1 as “platelet dust.” Since then, numerous studies have reported the in vitro release of vesicles from activated or apoptotic cells and their presence in human plasm...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2006
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.0000231507.00962.b5